J Pathol Transl Med.  2018 May;52(3):195-197. 10.4132/jptm.2017.05.15.

Expression of CD34 and β-Catenin in Malignant Rhabdoid Tumor of the Liver Mimicking Proximal-Type Epithelioid Sarcoma

• Cho WC
• Balarezo F

• KMID: 2412933
• DOI: http://doi.org/10.4132/jptm.2017.05.15

Abstract

No abstract available.

MeSH Terms

Liver*
Rhabdoid Tumor*
Sarcoma*

Figure

• 

  Fig. 1. Microscopic findings on liver biopsy. (A) The tumor displays malignant epithelioid cells with clear to amphophilic cytoplasm and small nucleoli with a focal organoid growth pattern. A rim of compressed non-neoplastic liver parenchyma is seen at the periphery of the tumor. (B, C) Areas of necrosis (B) and frequent mitoses (C, circle) within the tumor are also seen.

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  Fig. 2. Immunohistochemical analysis. (A) A diffuse and strong immunoreactivity (membranous) with β-catenin is seen in the tumor. (B) The tumor is also positive (patchy) for CD34. (C) Loss of nuclear INI1 expression is seen within the tumor.

Reference

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