J Pathol Transl Med.  2018 Mar;52(2):130-132. 10.4132/jptm.2016.11.17.

Osteosarcomatous Differentiation in Rebiopsy Specimens of Pulmonary Adenocarcinoma with EGFR-TKI Resistance

Affiliations
  • 1Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea. chungjh@snu.ac.kr
  • 2Department of Pathology, Seoul National University Hospital, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Adenocarcinoma*

Figure

  • Fig. 1. Histologic findings. First biopsy of case 1 (A) and case 2 (B). Microscopic finding of first biopsy reveals adenocarcinoma showing glandular differentiation. Rebiopsy of case 1 (C) and case 2 (D). Microscopic finding shows sarcomatous tumor cells producing osteoid (asterisks).

  • Fig. 2. Radiologic findings. Case 1 (A). Pelvic magnetic resonance imaging demonstrates left iliac metastases with ossification at the extraosseous soft tissue (arrow). Case 2 (B). Computed tomography reveals T2 and T5 vertebral bodies metastases.


Reference

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