Int J Thyroidol.  2017 Nov;10(2):107-113. 10.11106/ijt.2017.10.2.107.

Primary Sclerosing Mucoepidermoid Carcinoma with Eosinophilia of the Thyroid: Description of a Case and Review of the Literature

• Yang SI
• Park KK
• Yoo JY

• KMID: 2396815
• DOI: http://doi.org/10.11106/ijt.2017.10.2.107

Abstract

Primary sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) of the thyroid gland is a very rare disease. We present the clinical and histopathologic findings of a 37-year-old woman recently diagnosed with SMECE of the thyroid gland. The patient, clinically euthyroid, who presented with a neck swelling since last 2 years along. Fine needle aspiration cytology suggested thyroid papillary carcinoma. Total thyroidectomy, central neck dissection and right selective neck dissection were performed. Although SMECE is considered to be a relatively slow growing and non-aggressive tumor, occasional metastasis does occur. We report an additional case of SMECE, with metastasis to regional lymph nodes. Physicians should be aware of extended operation, including total thyroidectomy and/or neck node dissection for metastatic lesion of the neck node. More standardized treatment is likely to evolve in the future.

Keyword

Mucoepidermoid; Carcinoma; Eosinophilia; Thyroid gland

MeSH Terms

Adult
Biopsy, Fine-Needle
Carcinoma, Mucoepidermoid*
Carcinoma, Papillary
Eosinophilia*
Female
Humans
Lymph Nodes
Neck
Neck Dissection
Neoplasm Metastasis
Rare Diseases
Thyroid Gland*
Thyroidectomy