Ann Dermatol.  2017 Apr;29(2):237-238. 10.5021/ad.2017.29.2.237.

Intralymphatic Histiocytosis with Massive Interstitial Granulomatous Foci in a Patient with Rheumatoid Arthritis

• Tanaka M
• Funasaka Y
• Tsuruta K
• Kanzaki A
• Takahashi
• Saeki H

• KMID: 2394854
• DOI: http://doi.org/10.5021/ad.2017.29.2.237

Abstract

No abstract available.

MeSH Terms

Arthritis, Rheumatoid*
Histiocytosis*
Humans

Figure

• 

  Fig. 1 (A) Slightly tender erythematous nodules on the right knee which was slightly swollen. (B) The skin biopsy showed several irregularly dilated vessels which contained numerous mononuclear cells and interstitial histiocytic infiltrates in the upper dermis (H&E, ×40). (C) A dilated vessel which contained mononuclear cells (H&E, ×200). (D) Mononuclear cells stained positively for CD68 (anti CD68, ×200). (E) Endothelial cells lining the vessels were positive for D2-40 (anti D2-40, ×200). (F) A dense interstitial histiocytic infiltrate admixed with a few interspersed neutrophils which surrounded the degenerative collagen bundles (H&E, ×200).

Reference

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