Epidemiol Health.
2015;37:e2015031. 10.4178/epih/e2015031.
Analysis of survival data in thalassemia patients in Shiraz, Iran
- Affiliations
-
- 1Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
- 2Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran. m.hajipour.13@gmail.com
- 3Department of Epidemiology, Research Centre for Health Sciences, School of Health and Nutrition, Shiraz University of Medical Sciences, Shiraz, Iran.
- 4Department of Midwifery, School of Nursing and Midwifery, Fasa University of Medical Sciences, Fasa, Iran.
- 5Center for Disease Control and Prevention, Deputy of Health Services, Fasa University of Medical Sciences, Fasa, Iran.
- 6Department of Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.
- 7Islamic Azad University Khorasgan (Isfahan) Branch, Isfahan, Iran.
- KMID: 2380668
- DOI: http://doi.org/10.4178/epih/e2015031
Abstract
OBJECTIVES
The survival rate of thalassemia patients has not been conclusively established, and the factors associated with survival remain unclear. This study aimed to determine the survival rate of thalassemia among patients in southern Iran and to identify the factors associated with mortality from thalassemia.
METHODS
This retrospective cohort study was conducted based on a retrospective review of the medical records of 911 beta-thalassemia patients in 2014. Data analysis was conducted using the Kaplan-Meier method and Cox regression analysis.
RESULTS
Overall, 212 patients (23.3%) died, and 26.8% had thalassemia intermedia. The 20-year, 40-year, and 60-year survival rates were 85%, 63%, and 54%, respectively. Both crude and adjusted analyses found that education, marital status, ferritin levels, and comorbidities were related to mortality.
CONCLUSIONS
Sociodemographic and hematological factors were found to be significantly associated with the survival rate of thalassemia. Addressing these factors may help healthcare providers and physicians to provide the best possible care and to improve the survival rate.
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