J Rhinol.  2017 May;24(1):31-36. 10.18787/jr.2017.24.1.31.

The Impact of Nasal Polyposis on Olfactory Dysfunction in Chronic Rhinosinusitis

• Yoon HC
• Kim TM
• Joo JW
• Song IS
• Hong SN
• Yoo JH
• Lee SH

• KMID: 2379787
• DOI: http://doi.org/10.18787/jr.2017.24.1.31

Abstract

BACKGROUND AND OBJECTIVES
Olfactory disturbance is a major sinonasal symptom of chronic rhinosinusitis (CRS) with nasal polyps (NP). The aim of this study was to investigate the relationship between the severity of nasal polyposis and olfactory dysfunction in CRS.
SUBJECTS AND METHOD
A total of 277 subjects with CRS were included in this study. All participants were divided into four groups according to the size and degree of the nasal polyposis: the control group (no polyp; n=79); NP (nasal polyp) group I (both or unilateral simple polyposis; n=85); NP group II (unilateral diffuse polyposis; n=66); and NP group III (bilateral diffuse polyposis; n=47). We analyzed the relationships between the severity of nasal polyposis and olfactory dysfunction using both the Korean Version of the "Sniffin'Sticks" test (KVSS Test) II and the Questionnaire of Olfactory Disorders (QOD).
RESULTS
The KVSS Test II TDI score was significantly decreased in the bilateral diffuse polyposis group (NP group III=15.62±13.39) compared to the other polyp groups [control group=25.04±9.67 (p<0.001); NP group I=21.67±11.18 (p=0.005); NP group II=21.51±10.85 (p=0.008)]. However, there were no significant differences in the KVSS Test II TDI score between the control group and NP groups I and II. For the QOD_NS score, only NP group III (11.51±9.87) had significantly increased values compared to the control group [8.42±12.27 (p=0.015)].
CONCLUSION
These results suggest that bilateral diffuse nasal polyposis is related to significant olfactory dysfunction in CRS.

Keyword

Nasal polyp; Rhinosinusitis; Olfaction

MeSH Terms

Methods
Nasal Polyps
Polyps
Smell

Figure

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  Fig. 1. Meltzer score used to classify nasal polyp grade. 0: no visible NP, 1: small amount of polypoid disease confined within the middle meatus, 2: multiple polyps occupying the middle meatus, 3: polyps extending beyond the middle meatus, 4: poly.

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  Fig. 2. NP groups and KVSS TDI. Bilateral diffuse polyposis group ( NP group IV, KVSS Test II TDI score=15.62±13.39) have significantly decreased in KVSS Test II TDI score compared to other polyposis groups [ control group=25.04±9.67 ( p=0.008)]; NP gro.

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