1. Clavell LA, Gelber RD, Cohen HJ, et al. Four-agent induction and intensive asparaginase therapy for treatment of childhood acute lymphoblastic leukemia. N Engl J Med. 1986; 315:657–663. PMID:
2943992.
Article
2. Roesmann A, Afify M, Panse J, Eisert A, Steitz J, Tolba RH. L-carnitine ameliorates L-asparaginase-induced acute liver toxicity in steatotic rat livers. Chemotherapy. 2013; 59:167–175. PMID:
24192517.
Article
3. Alshiekh-Nasany R, Douer D. L-Carnitine for treatment of pegasparaginase-induced hepatotoxicity. Acta Haematol. 2016; 135:208–210. PMID:
26841296.
Article
4. Al-Nawakil C, Willems L, Mauprivez C, et al. Successful treatment of L-asparaginase-induced severe acute hepatotoxicity using mitochondrial cofactors. Leuk Lymphoma. 2014; 55:1670–1674. PMID:
24090500.
5. Pratt CB, Johnson WW. Duration and severity of fatty metamorphosis of the liver following L-asparaginase therapy. Cancer. 1971; 28:361–364. PMID:
5109448.
Article
6. Durden DL, Salazar AM, Distasio JA. Kinetic analysis of hepatotoxicity associated with antineoplastic asparaginases. Cancer Res. 1983; 43:1602–1605. PMID:
6339039.
7. Tsuji F, Miyake Y, Aono H, Kawashima Y, Mita S. Effects of bucillamine and N-acetyl-L-cysteine on cytokine production and collagen-induced arthritis (CIA). Clin Exp Immunol. 1999; 115:26–31. PMID:
9933417.
Article
8. Firpi RJ, Nelson DR. Viral hepatitis: manifestations and management strategy. Hematology Am Soc Hematol Educ Program. 2006; 375–380. PMID:
17124086.
Article
9. Nazer LH, Nazer HM. Drug-induced liver injury. In : Elzouki AY, Harfi HA, Nazer H, Oh W, Stapleton FB, Whitley RJ, editors. Textbook of clinical pediatrics. 2nd ed. New York, NY: Springer;2012. p. 2113–2117.
10. Zimmerman HJ. Hepatotoxicity: the adverse effects of drugs and other chemicals on the liver. 2nd ed. Philadelphia, PA: Lippincott Williams & Wilkins;1999. p. 673–709.
11. Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, Lemasters JJ. Mechanisms of hepatotoxicity. Toxicol Sci. 2002; 65:166–176. PMID:
11812920.
Article
12. Marí M, Morales A, Colell A, García-Ruiz C, Kaplowitz N, Fernandez-Checa JC. Mitochondrial glutathione: features, regulation and role in disease. Biochim Biophys Acta. 2013; 1830:3317–3328. PMID:
23123815.
Article
13. Baumgardner JN, Shankar K, Hennings L, Albano E, Badger TM, Ronis MJ. N-acetylcysteine attenuates progression of liver pathology in a rat model of nonalcoholic steatohepatitis. J Nutr. 2008; 138:1872–1879. PMID:
18806095.
Article
14. Samuhasaneeto S, Thong-Ngam D, Kulaputana O, Patumraj S, Klaikeaw N. Effects of N-acetylcysteine on oxidative stress in rats with non-alcoholic steatohepatitis. J Med Assoc Thai. 2007; 90:788–797. PMID:
17487136.
15. Kaya I, Citil M, Sozmen M, Karapehlivan M, Cigsar G. Investigation of protective effect of L-carnitine on L-asparaginase-induced acute pancreatic injury in male Balb/c mice. Dig Dis Sci. 2015; 60:1290–1296. PMID:
25502333.
Article