Korean J Ophthalmol.  2016 Aug;30(4):309-310. 10.3341/kjo.2016.30.4.309.

Verrucous Carcinoma of the Eyelid

Affiliations
  • 1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. khwarg@snu.ac.kr
  • 2Department of Ophthalmology, Armed Forces Capital Hospital, Seongnam, Korea.
  • 3Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 4Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Aged
Biopsy
Carcinoma, Verrucous/*diagnosis
Diagnosis, Differential
Eyelid Neoplasms/*diagnosis
Eyelids/*diagnostic imaging
Female
Humans

Figure

  • Fig. 1 (A) External clinical photographs of the presenting patient showing a 5 × 5-mm-sized mass consisting of a dome-shaped base, horn-shaped top and hyperkeratinized tip in the right medial canthal area. (B) Twenty days after the initial exam, the mass has increased in height. (C) The completely excised mass reveals superficial hyperkeratosis and "elephant feet-like" downgrowth (black arrows) compressing the underlying connective tissue (H&E, ×10). (D) Note the expansile, pushing border (white arrows), which is a diagnostic feature of verrucous carcinoma (H&E, ×100). (E) High-power view demonstrates well-differentiated squamous epithelium with minimal atypia in some area (dotted circle) (H&E, ×400). (F) Good functional and esthetic results were observed at 7 months after surgery.


Reference

1. Koch H, Kowatsch E, Hodl S, et al. Verrucous carcinoma of the skin: long-term follow-up results following surgical therapy. Dermatol Surg. 2004; 30:1124–1130.
2. Mak ST, Io IY, Tse RK. Verrucous carcinoma: a rare tumor of the eyelid. Ophthal Plast Reconstr Surg. 2011; 27:e32–e34.
3. Tzili N, El Yamouni O, El Khaoua M, et al. Verrucous squamous carcinoma of the eyelid: report of a case. Pan Afr Med J. 2014; 18:93.
4. Woolgar JA, Triantafyllou A. Pitfalls and procedures in the histopathological diagnosis of oral and oropharyngeal squamous cell carcinoma and a review of the role of pathology in prognosis. Oral Oncol. 2009; 45:361–385.
5. Schwartz RA. Verrucous carcinoma of the skin and mucosa. J Am Acad Dermatol. 1995; 32:1–21.
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