J Gastric Cancer.  2011 Dec;11(4):200-205.

Aging over 70 Years Is Not a Decisively Dismal Prognostic Factor in Gastric Cancer Surgery

Affiliations
  • 1Department of Surgery, Korea University College of Medicine, Seoul, Korea. kugspss@korea.ac.kr

Abstract

PURPOSE
Gastric cancer has a high incidence and mortality rate in Korea. Despite a growing older population and an increase in the number of older patients with gastric cancer, the older patients are not willing to undergo surgery due to their operative risks. Hence, to determine the clinical characteristics and outcomes of gastric cancer surgery for them, we investigate factors influencing the treatment decision.
MATERIALS AND METHODS
Between January 1996 and December 2005, a total of 1,519 patients were classified into two groups; the younger age group between 41 and 69 years of age, and the older age group of 70 years or older. The analysis conducted included patient characteristics, accompanying disorders, related American Society of Anesthesiologists (ASA) grade, pathological characteristics and survival rate for each age group.
RESULTS
Significant differences were found in the ASA grade (P<0.001) and the number of accompanying disorders (P<0.001) between the two groups. The average length of hospital stay after surgery was 14.5 days in the younger age group, and 13.3 days in the older age group (P=0.065). The average survival time was 47.5 months in the younger age group, and 43.2 months in the older age group (P<0.001).
CONCLUSIONS
This study demonstrated that there was more number of accompanying disorders with a high surgical risk in the older age group. However, there was no significant difference between the older and younger age groups in terms of the incidence of complications, under the given disease conditions and if proper management was provided.

Keyword

Stomach neoplasms; Aged; Survival

MeSH Terms

Aged
Aging
Humans
Incidence
Korea
Length of Stay
Stomach Neoplasms
Survival Rate

Figure

  • Fig. 1 Survival curves according to age group.


Reference

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011. 61:69–90.
Article
2. Jung KW, Park S, Kong HJ, Won YJ, Lee JY, Park EC, et al. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2008. Cancer Res Treat. 2011. 43:1–11.
Article
3. The Information Committee of the Korean Gastric Cancer Association. 2004 Nationwide Gastric Cancer Report in Korea. J Korean Gastric Cancer Assoc. 2007. 7:47–54.
4. Mitsudomi T, Matsusaka T, Wakasugi K, Takenaka M, Kume K, Fujinaga Y, et al. A clinicopathological study of gastric cancer with special reference to age of the patients: an analysis of 1,630 cases. World J Surg. 1989. 13:225–230.
Article
5. Washington K. 7th edition of the AJCC cancer staging manual: stomach. Ann Surg Oncol. 2010. 17:3077–3079.
Article
6. Kim HK, Lee CH, Choi KH, Lee SD, Seo JK. Clinical analysis of surgery in the elderly. J Korean Surg Soc. 1990. 39:792–799.
7. Gosain A, DiPietro LA. Aging and wound healing. World J Surg. 2004. 28:321–326.
Article
8. Lee YA, Jung GA, Min YD. Operative treatment of patients over 75 years old with gastric cancer. J Korean Gastric Cancer Assoc. 2005. 5:217–221.
Article
9. Chung HY, Yu W. Characteristics of gastric carcinomas in two extreme age groups. J Korean Gastric Cancer Assoc. 2002. 2:200–204.
Article
10. Song RJ, Kim SP, Min YD. Clinicopathologic characteristics and the prognosis of gastric cancer patients at both extremes of age. J Korean Gastric Cancer Assoc. 2007. 7:67–73.
Article
11. Shin DG, Seong SH, Kim WS, Kim DS. The effect of old age on the development of postoperative complication in surgery for gastric carcinoma. J Korean Surg Soc. 2005. 69:455–458.
12. Choi NK, Youn KE, Heo DS, Lee SM, Kim Y, Park BJ. Stomach cancer incidence, mortality and survival rate in Korean elderly pharmacoepidemiologic cohort (KEPEC) in 1994~1998. Cancer Res Treat. 2003. 35:383–390.
Article
13. Jung KW, Park S, Kong HJ, Won YJ, Boo YK, Shin HR, et al. Cancer statistics in Korea: incidence, mortality and survival in 2006-2007. J Korean Med Sci. 2010. 25:1113–1121.
Article
14. Mohri Y, Omori Y, Hiro J, Yokoe T, Konishi N, Tanaka K, et al. Clinicopathological features and prognosis of gastric cancer patients > or =75 years of age after laparotomy. Int Surg. 2009. 94:38–42.
15. Saif MW, Makrilia N, Zalonis A, Merikas M, Syrigos K. Gastric cancer in the elderly: an overview. Eur J Surg Oncol. 2010. 36:709–717.
Article
16. Cho GS, Kim W, Kim HH, Ryu SW, Kim MC, Ryu SY. Multicentre study of the safety of laparoscopic subtotal gastrectomy for gastric cancer in the elderly. Br J Surg. 2009. 96:1437–1442.
Article
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