Korean J Vet Res.  2016 Sep;56(3):177-181. 10.14405/kjvr.2016.56.3.177.

Establishment of normal reference of radiological morphology of renal artery in mini-pigs by renal angiography

Affiliations
  • 1PWG Genetics Pte. Ltd., Singapore 638117, Singapore. pwggeneticslisa@gmail.com
  • 2Handok Kalos Medical Inc., Seoul 06235, Korea.

Abstract

Mini-pigs have been widely employed in preclinical studies to explore new therapeutic strategies for diseases of the human urinary system; however, the normal reference of the renal artery has not been clearly investigated in the mini-pig model. Therefore, we aimed to establish a normal reference of the radiological morphology of the renal artery in mini-pigs by renal angiography via catheterization of the carotid artery. The renal angiographies obtained from 15 mini-pigs were evaluated to determine the orifice from the aorta, facing direction, size and the number of branches of renal arteries. Cranio-laterally facing renal arteries with 2 distal branches were mainly observed in the renal artery of mini-pigs. Both sides of the renal artery presented symmetrical sizes; however, the right renal artery orifice from the aorta was located more cranially than the left counterpart. The results of this study will contribute to radiological diagnosis of the renal artery as well as preclinical studies of mini-pigs.

Keyword

carotid artery catheterization; mini-pig normal reference; radiological morphology; renal angiography; renal artery intervention

MeSH Terms

Angiography*
Aorta
Carotid Arteries
Catheterization
Catheters
Diagnosis
Humans
Renal Artery*
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