Chonnam Med J.
2017 Jan;53(1):28-36. 10.4068/cmj.2017.53.1.28.
Versatile Functions of Caveolin-1 in Aging-related Diseases
- Affiliations
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- 1Deparment of Life Science, ThaiNguyen University of Science, TanThinh Ward, ThaiNguyen, VietNam.
- 2Department of Biochemistry, Chonnam National University Medical School, Gwangju, Korea. kacho@jnu.ac.kr
- KMID: 2367337
- DOI: http://doi.org/10.4068/cmj.2017.53.1.28
Abstract
- Caveolin-1 (Cav-1) is a trans-membrane protein that is a major component of the caveolae structure on the plasma membrane. Cav-1 is involved in the regulation of various cellular processes, including cell growth, differentiation, endocytosis, and in particular it has been implied in cellular senescence. Here we review current knowledge about Cav-1 in cellular signaling and discuss the role of Cav-1 in aging-related diseases.
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