Int Neurourol J.
2016 Jun;20(2):101-106. 10.5213/inj.1632664.332.
Implantable Devices for Sustained, Intravesical Drug Delivery
- Affiliations
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- 1Institute of Medical & Biological Engineering, Medical Research Center, Seoul National University, Seoul, Korea. ybchoy@snu.ac.kr
- 2Department of Biomedical Engineering, Seoul National University College of Medicine, Seoul, Korea.
- 3Interdisciplinary Program in Bioengineering, College of Engineering, Seoul National University, Seoul, Korea.
- KMID: 2365740
- DOI: http://doi.org/10.5213/inj.1632664.332
Abstract
- In clinical settings, intravesical instillation of a drug bolus is often performed for the treatment of bladder diseases. However, it requires repeated instillations to extend drug efficacy, which may result in poor patient compliance. To alleviate this challenge, implantable devices have been developed for the purpose of sustained, intravesical drug delivery. In this review, we briefly summarize the current trend in the development of intravesical drug-delivery devices. We also introduce the most recently developed devices with strong potential for intravesical drug-delivery applications.
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