Ann Dermatol.  1995 Jan;7(1):82-85. 10.5021/ad.1995.7.1.82.

Infantile Acute Hemorrhagic Edema

Abstract

We report a case of infantile acute hemorrhagic edema in a 15-month-old boy. The patient showed multiple, bean to walnut-sized, red to purple-colored, indurated purpura with a cockade pattern on the face, earlobes, and extremities. Edema of the hands, feet, and earlobes was also observed. Laboratory examinations showed thrombocytosis, decreased serum CH50, and ketone in the urine. A skin biopsy taken from indurated purpura on the lower leg exhibited findings of acute leukocytoclastic vasculitis. Direct immunofluorescence examination showed deposition of IgM along the dermo-epidermal junction and C3 in the dermal vessel walls. With-out specific management except for fluid therapy to correct dehydration, the skin lesions cleared completely in 2 weeks, and recurrence has not observed.

Keyword

Acute leukocytoclastic vasculitis; Indurated purpura with cockade pattern; Infantile acute hemorrhagic edema

MeSH Terms

Biopsy
Dehydration
Edema*
Extremities
Fluid Therapy
Fluorescent Antibody Technique, Direct
Foot
Hand
Humans
Immunoglobulin M
Infant
Leg
Male
Purpura
Recurrence
Skin
Thrombocytosis
Vasculitis
Immunoglobulin M
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