J Korean Radiol Soc.  1990 Dec;26(6):1284-1290. 10.3348/jkrs.1990.26.6.1284.

Clinical application of intravascular administration of non-ionic, low osmolar contrast agent, ioversol(Optiray320) and its side effects comparison with meglumine iothalamate

• Hong HS
• Kim DH
• Lee HK
• Chung MC
• Choi DL
• Kwon KH
• Kim KJ

• KMID: 2358791
• DOI: http://doi.org/10.3348/jkrs.1990.26.6.1284

Abstract

Ioversol, the non-ionic, low osmolar contrast agent has been well characterized chemically and in terms ofvasic toxicity testing. Ioversol has a fomula similar to that of other nonionic agent. We review the results ofintravascular use of this contast agent, compared ionic contrast media(Meglumine Iothalamate(Conray60) ). Eachstudy was assessed for imaging quality, and before and after contrast administration and were observed foroccurrence of side effects. A small number of side effects were reported but no clinically significant sequellaein Ioversol group and much less vital sign changes compared with Conary group. There were no significant changesin vital signs related to the use of Ioversol, and no significant alterations in the renal function parameter orother blood chemistry and hematology measurement were encountered in both contrast media. In most cases, the imagequalities were good. in conclusion, Ioversol is safe, well tolerated and efficious for use in intravascularcontrast agent, and less vital sign changes and side effect than ionic Meglumine iothalamte, and Ioversol islikely to provide a useful and acceptable alternative to other low osmolar and nonionic contrast agents.

MeSH Terms

Chemistry
Contrast Media
Hematology
Iothalamate Meglumine*
Meglumine*
Toxicity Tests
Vital Signs
Contrast Media
Iothalamate Meglumine
Meglumine