Korean J Anesthesiol.  1979 Jun;12(2):129-133.

Clinical Effects of Hydroxyzine Hydrochloride as a Premedicant

Affiliations
  • 1Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Hydroxyzine hydrochloride, a minor tranquilizer and a ataratic, was tested clinically for effectiveness as a premedicant separate dosages of 1 and 2 mg/kg. Each 30 patients were in the physical status class 1 and 2 by A.S.A. classification, and the age distribution was from 20 to 60 years. The following results were obtained. 1) Emotionally calm response was seen in 70% in the hydroxyzine 1 mg/kg (group 1), and in 93.3%, in the 2 mg/kg (group 2). 2) Mental alertness was seen in 86. 6% in group 1, and in 66. 6% in group 2. 3) Complications after premedication were chilling and shivering, hypertension, nausea, and headache, and were not serious. Therefore this premedication was satisfactory in most cases, especially in group 2.


MeSH Terms

Age Distribution
Classification
Headache
Humans
Hydroxyzine*
Hypertension
Nausea
Premedication
Shivering
Hydroxyzine
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