J Korean Ophthalmol Soc.  2016 Oct;57(10):1521-1526. 10.3341/jkos.2016.57.10.1521.

Efficacy of Strip Meniscometry for Dry Eye Syndrome Diagnosis

Affiliations
  • 1The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. taeimkim@gmail.com
  • 2Corneal Dystrophy Research Institute, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

PURPOSE
To evaluate the efficacy of strip meniscometry test for dye eye syndrome (DES) by measuring the correlation between strip meniscometry and conventional test measurements.
METHODS
All subjects were examined using the Schirmer test, tear breakup time (TBUT) and strip meniscometry using SMTube (Echo Electricity Co., Ltd., Fukushima, Japan). Tear meniscus height (TMH), tear meniscus depth (TMD) and tear meniscus area (TMA) were measured using Fourier-domain optical coherence tomography. The DES group (n = 46 eyes) was compared with the normal group (n = 30 eyes) and correlation was assessed using Spearman's correlation coefficient.
RESULTS
Strip meniscometry measurement was significantly correlated with Schirmer score (r = 0.6080, p < 0.01), TBUT (r = 0.5980, p < 0.01), TMH (r = 0.6210, p < 0.01), TMD (r = 0.6080, p < 0.01) and TMA (r = 0.6370, p < 0.01). Strip meniscometry was significantly lower in the DES group (4.58 ± 1.94 mm) than the normal group (7.07 ± 2.61 mm, p < 0.05).
CONCLUSIONS
Strip meniscometry was significantly correlated with other conventional test measurements for dry eye syndrome. Strip meniscometry is less time consuming and a less invasive method than the Schirmer test. Strip meniscometry could be an efficient tool to evaluate patients with dry eye syndrome in a clinical setting.

Keyword

Dry eye syndrome; Schirmer test; Strip meniscometry

MeSH Terms

Diagnosis*
Dry Eye Syndromes*
Electricity
Humans
Methods
Tears
Tomography, Optical Coherence

Figure

  • Figure 1. Optical coherence tomography image of the lower tear meniscus showing the tear meniscus height, depth and area. Measurements of tear meniscus height (TMH), tear meniscus depth (TMD), tear meniscus area (TMA) were performed using RTVue software.

  • Figure 2. The image of Strip meniscometry tube® (SMTube; Echo Electricity Co., Ltd., Fukushima, Japan). The strip ni-trocellulose membranes have a pore size of 8 μ m. Natural blue dye 1 is printed at the tip of the strip. A millimeter and a numeric scale of up to 35 mm is printed on the both sides.


Reference

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