Korean J Phys Anthropol.  2016 Sep;29(3):99-103. 10.11637/kjpa.2016.29.3.99.

The Prevalence and Genetic Pattern of Clinodactyly in Korean Populations

• Song D
• Chung J
• Shin HG
• Jung SJ
• Lee JH

• KMID: 2354349
• DOI: http://doi.org/10.11637/kjpa.2016.29.3.99

Abstract

Clinodactyly, as rare congenital malformation, refers to a curvature of a digit in a radial or ulnar direction in the coronal plane. The abnormality is inherited as an autosomal dominant trait. And its frequency was low, however, it was higher by accompanying other congenital anomaly. In present study, the frequency and genetic characteristics of clinodactyly were investigated. In 100 family (382 peoples), clinodactyly was found in 4.7% (n=18). All clinodactyly were bilateral and it was more frequent in female (6.8%) than male (2.6%), without statistical difference (p=0.056). Its inheritance was autosomal dominant trait in 80% (4/5) families, however, one family did not have any inheritance pattern. We described the frequency and clinical implication of clinodactyly, and this description will be lead to an improved understanding of its spectrum and inheritance.

Keyword

Clinodactyly; Autosomal dominant; Hand deformity; Smartphone pinky

MeSH Terms

Female
Hand Deformities
Humans
Inheritance Patterns
Male
Prevalence*
Wills

Figure

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  Fig. 1. Representative image of clinodactyly of the fifth fingers.

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  Fig. 2. Example pedigree for a family with clinodactyly (a) Autosomal dominant (b) No inheritance fashion.

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  Fig. 3. Smartphone pinky.

Reference

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