J Korean Med Assoc.  2016 Aug;59(8):637-643. 10.5124/jkma.2016.59.8.637.

Glaucoma Schlemm's canal stent insertion: a systematic review

• Jo S

• KMID: 2349841
• DOI: http://doi.org/10.5124/jkma.2016.59.8.637

Abstract

Schlemm's canal stent insertion is a procedure for controlling the intraocular pressure by inserting a stent in the anterior chamber in patients with open-angle glaucoma. The objective of this review is to evaluate the safety and effectiveness of Schlemm's canal stent insertion for glaucoma. Searches of key databases, including 8 Korean databases, Medline, Embase, and Cochrane Library, were searched. Among 249 articles located in the search, a total of 14 studies (4 randomized controlled trials and 10 case series) were included in this review. Two review authors independently selected the studies and assessed their quality. On the basis of current data, we recommend that Schlemm's canal stent insertion is safe and effective for reducing intraocular pressure and the number of anti-glaucoma medications being administered for patients with open angle glaucoma.

Keyword

Glaucoma; Stent insertion; Intraocular pressure; Review

MeSH Terms

Anterior Chamber
Glaucoma*
Glaucoma, Open-Angle
Humans
Intraocular Pressure
Stents*

Figure

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  Figure 1 Flow chart of literature selection process.

Reference

1. Blumberg D, Skaat A, Liebmann JM. Emerging risk factors for glaucoma onset and progression. Prog Brain Res. 2015; 221:81–101.

2. Tian K, Shibata-Germanos S, Pahlitzsch M, Cordeiro MF. Current perspective of neuroprotection and glaucoma. Clin Ophthalmol. 2015; 9:2109–2118.

3. Choi JH, Lee KJ. The change of binocular visual function in mild, moderate and severe glaucoma patients. Korean J Vis Sci. 2015; 17:299–309.

4. Choi JH, Park JW, Park SW. The study of ocular side effects after the use of anti-Glaucoma topical medication. J Korean Ophthalmol Soc. 2013; 54:745–751.

5. Oh EK, Lee EJ, Jeoung JW, Kim SH, Kim TW, Park KH, Kim DM. Long-term outcomes of trabeculectomy in Korean patients with juvenile open-angle glaucoma. J Korean Ophthalmol Soc. 2014; 55:252–260.

6. Wellik SR, Dale EA. A review of the iStent trabecular micro-bypass stent: safety and efficacy. Clin Ophthalmol. 2015; 9:677–684.

7. Gedde SJ, Herndon LW, Brandt JD, Budenz DL, Feuer WJ, Schiffman JC. Tube Versus Trabeculectomy Study Group. Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up. Am J Ophthalmol. 2012; 153:804–814.e1.

8. Richter GM, Coleman AL. Minimally invasive glaucoma surgery: current status and future prospects. Clin Ophthalmol. 2016; 10:189–206.

9. Arriola-Villalobos P, Morales-Fernandez L, Martinez-de-la-Casa JM, Garcia-Feijoo J. Effects of Glaukos trabecular stent in the treatment of glaucoma. Eur Ophthalmic Rev. 2013; 7:10–13.

10. Craven ER. Trabecular micro-bypass shunt (iStent): basic science, clinical, and future). Middle East Afr J Ophthalmol. 2015; 22:30–37.

11. Scottish Intercollegiate Guidelines Network. Methodology checklists [Internet]. Edinburgh: Scottish Intercollegiate Guidelines Network;2011. cited 2016 Mar 10. Available from: http://www.sign.ac.uk/methodology/checklists.html.

12. Fea AM, Belda JI, Rękas M, Junemann A, Chang L, Pablo L, Voskanyan L, Katz LJ. Prospective unmasked randomized evaluation of the iStent inject versus two ocular hypotensive agents in patients with primary open-angle glaucoma. Clin Ophthalmol. 2014; 8:875–882.

13. Craven ER, Katz LJ, Wells JM, Giamporcaro JE. iStent Study Group. Cataract surgery with trabecular micro-bypass stent implantation in patients with mild-to-moderate open-angle glaucoma and cataract: two-year follow-up. J Cataract Refract Surg. 2012; 38:1339–1345.

14. Fea AM. Phacoemulsification versus phacoemulsification with micro-bypass stent implantation in primary open-angle glaucoma: randomized double-masked clinical trial. J Cataract Refract Surg. 2010; 36:407–412.

15. Fernandez-Barrientos Y, Garcia-Feijoo J, Martinez-de-la-Casa JM, Pablo LE, Fernandez-Perez C, Garcia Sanchez J. Fluorophotometric study of the effect of the glaukos trabecular micro-bypass stent on aqueous humor dynamics. Invest Ophthalmol Vis Sci. 2010; 51:3327–3332.

16. Ahmed II, Katz LJ, Chang DF, Donnenfeld ED, Solomon KD, Voskanyan L, Samuelson TW. Prospective evaluation of microinvasive glaucoma surgery with trabecular micro-bypass stents and prostaglandin in open-angle glaucoma. J Cataract Refract Surg. 2014; 40:1295–1300.

17. Voskanyan L, Garcia-Feijoo J, Belda JI, Fea A, Junemann A, Baudouin C. Synergy Study Group. Prospective, unmasked evaluation of the iStent inject system for open-angle glaucoma: synergy trial. Adv Ther. 2014; 31:189–201.

18. Arriola-Villalobos P, Martinez-de-la-Casa JM, Diaz-Valle D, Garcia-Vidal SE, Fernandez-Perez C, Garcia-Sanchez J, Garcia-Feijoo J. Mid-term evaluation of the new Glaukos iStent with phacoemulsification in coexistent open-angle glaucoma or ocular hypertension and cataract. Br J Ophthalmol. 2013; 97:1250–1255.

19. Arriola-Villalobos P, Martinez-de-la-Casa JM, Diaz-Valle D, Fernandez-Perez C, Garcia-Sanchez J, Garcia-Feijoo J. Combined iStent trabecular micro-bypass stent implantation and phacoemulsification for coexistent open-angle glaucoma and cataract: a long-term study. Br J Ophthalmol. 2012; 96:645–649.

20. Belovay GW, Naqi A, Chan BJ, Rateb M, Ahmed II. Using multiple trabecular micro-bypass stents in cataract patients to treat open-angle glaucoma. J Cataract Refract Surg. 2012; 38:1911–1917.

21. Spiegel D, Wetzel W, Neuhann T, Stuermer J, Hoeh H, Garcia-Feijoo J, Martinez-De-La-Casa JM, Garcia-Sanchez J. Coexistent primary open-angle glaucoma and cataract: interim analysis of a trabecular micro-bypass stent and concurrent cataract surgery. Eur J Ophthalmol. 2009; 19:393–399.

22. Patel I, de Klerk TA, Au L. Manchester istent study: early results from a prospective UK case series. Clin Experiment Ophthalmol. 2013; 41:648–652.

23. Vandewalle E, Zeyen T, Stalmans I. The iStent trabecular micro-bypass stent: a case series. Bull Soc Belge Ophtalmol. 2009; (311):23–29.

24. Spiegel D, Wetzel W, Haffner DS, Hill RA. Initial clinical experience with the trabecular micro-bypass stent in patients with glaucoma. Adv Ther. 2007; 24:161–170.

25. Buchacra O, Duch S, Milla E, Stirbu O. One-year analysis of the iStent trabecular micro-bypass in secondary glaucoma. Clin Ophthalmol. 2011; 5:321–326.