Ann Dermatol.  2016 Aug;28(4):519-521. 10.5021/ad.2016.28.4.519.

Cutaneous Metastasis of Rhabdomyosarcoma Originated from Maxillary Sinus in a Young Adult Female

• Kim JH
• Oh S
• Jun JY
• Shim JH
• Park JH
• Lee DY

• KMID: 2344834
• DOI: http://doi.org/10.5021/ad.2016.28.4.519

Abstract

No abstract available.

MeSH Terms

Female*
Humans
Maxillary Sinus*
Neoplasm Metastasis*
Rhabdomyosarcoma*
Young Adult*

Figure

• 

  Fig. 1 Multiple, erythematous nodules on the upper and lower inner quadrants of the left breast.

• 

  Fig. 2 Histological features of the skin nodule. (A) Dense infiltration of primitive ovoid neoplastic cells through the dermal collagen bundles (H&E, ×40). (B) Atypical cells with darkly stained hyperchormatic nuclei and scant cytoplasm (H&E, ×200). Positive immunostaining for (C) vimentin, (D) myoglobin, (E) desmin, and (F) myogenin, but negative for (G) MyoD1 (C~G: ×200).

Reference

1. Egas-Bejar D, Huh WW. Rhabdomyosarcoma in adolescent and young adult patients: current perspectives. Adolesc Health Med Ther. 2014; 5:115–125.

2. Elomrani F, Touri S, Ouziane I, Berrada N, Boutayeb S, Mrabti H, et al. Orbital rhabdomyosarcoma with skin metastasis: a case report. BMC Res Notes. 2014; 7:670.

3. Marburger TB, Gardner JM, Prieto VG, Billings SD. Primary cutaneous rhabdomyosarcoma: a clinicopathologic review of 11 cases. J Cutan Pathol. 2012; 39:987–995.

4. Shimizu S, Yasui C, Minauchi K, Tsuchiya K. Metastatic rhabdomyosarcoma of the skin. J Am Acad Dermatol. 2008; 58:S118–S120.

5. Folpe AL. MyoD1 and myogenin expression in human neoplasia: a review and update. Adv Anat Pathol. 2002; 9:198–203.