J Korean Soc Radiol.  2016 Aug;75(2):138-142. 10.3348/jksr.2016.75.2.138.

Malignant Granular Cell Tumor of the Abdominal Wall Mimicking Desmoid Tumor: A Case Report with CT Imaging Findings and Literature Review

• Yoon J
• Ahn SE
• Lee DH
• Park SJ
• Moon SK
• Lim JW

• KMID: 2344804
• DOI: http://doi.org/10.3348/jksr.2016.75.2.138

Abstract

Granular cell tumors (GCTs) are extremely rare mesenchymal neoplasms of Schwann cell origin. Malignant GCTs (MGCTs) comprise 0.5-2% of all GCTs. In the present report, we describe a case of a 66-year-old man with MGCT of the abdominal wall. The patient visited our hospital due to a recently growing palpable soft tissue mass in the abdominal wall. Computed tomography scan revealed a 4.3 × 4.1 × 2.9 cm sized mass arising from the left abdominal wall, which was contemplated as a desmoid tumor before surgical excision. Histopathological examination confirmed MGCT.

MeSH Terms

Abdominal Wall*
Aged
Fibroma
Fibromatosis, Aggressive*
Granular Cell Tumor*
Humans

Figure

• 

  Fig. 1 A 66-year-old man with a malignant granular cell tumor of the abdominal wall muscle. A. The axial contrast-enhanced abdominal CT scan reveals a well-defined, relatively homogeneous enhancing solid mass in the left anterolateral abdominal wall, arising from the left internal oblique and transverse abdominal muscles. A focal ill-defined low attenuated portion can be seen in the mass (arrow). B. The coronal image demonstrates a focally ill-defined mass at the inferior edge (arrow). C. Hematoxylin-eosin staining (× 400) shows tumor cells with abundant cytoplasm and intracytoplasmic granules (arrow). D. Periodic acid-Schiff stain (× 400) shows tumor cells with positive purple-magenta staining. E. Staining for S-100 (× 150) shows tumor cells with positive red-brick color staining.

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