J Korean Neuropsychiatr Assoc.  2006 Mar;45(2):145-151.

The Association of Nocturnal Sleep Pattern with the Quality of Life in Chronic Renal Failure Patients on Hemodialysis

• Park JI
• Kim SJ
• Jung HH
• Lee JH

Abstract

OBJECTIVES
We aimed to compare the quality of life (QOL) between patients with chronic renal failure (CRF) and normal control subjects, and to examine the relationship of QOL with the sleep characteristics in CRF patients.
METHODS
The Epworth Sleepiness Scale (ESS) and World Health Organization Quality of Life assessment instrument-Brief form (WHOQOL-BREF) were administered to 26 CRF patients (male: 20 Age: 53.5+/-8.7 years) and 26 age- and sex-matched control subjects (male: 20 Age: 51.9+/-9.7 years). Nocturnal polysomnography (Embla S7000 Medcare system, New York, USA) was conducted for 26 CRF patients to measure the sleep parameters.
RESULTS
The total score and all the subscale scores of WHOQOL-BREF in the CRF patients were lower than those of the control subjects (p<0.01). The amount of rapid eye movement sleep (REMS) was positively correlated with the physical health domain score (r=0.457). In addition, there were significantly negative correlations of the respiratory disturbance index and hypopnea index with the physical health domain score (r=-0.415, -0.616).
CONCLUSION
The QOL of CRF patients was lower than that of the normal controls. Particularly, lower QOL of the physical health domain in CRF patients was associated with greater severity of sleep breathing disorder and lower amount of REMS.

Keyword

Chronic renal failure; Quality of life; Polysomnography

MeSH Terms

Humans
Kidney Failure, Chronic*
Polysomnography
Quality of Life*
Renal Dialysis*
Respiration
Sleep, REM
World Health Organization