J Korean Ophthalmol Soc.  2012 Apr;53(4):528-535.

Quality of Life Assessment in Patients with Wet Age-Related Macular Degeneration

Affiliations
  • 1Deparment of Ophthalmology, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. eye-su@hanmail.net

Abstract

PURPOSE
This study was performed to assess the relationship between wet age-related macular degeneration (AMD) and quality of life (QOL).
METHODS
The National Eye Institute Visual Functioning Questionnaire 25 was administered to 27 wet AMD patients under treatment at Kangbuk Samsung hospital ophthalmology clinic. The relationship between wet AMD and QOL was analyzed according to age, visual acuity status and general health status.
RESULTS
Older patients and those with hypertension had significantly lower mean scores for general vision, near vision, distance vision, vision-specific role difficulties and dependency compared to their younger and normotensive counterparts. Patients with cataracts had lower mean scores for general vision and color vision than those without, and patients with unilateral AMD had higher mean scores on the driving subscale of the questionnaire.
CONCLUSIONS
Wet AMD has a substantial impact on patient quality of life. A comprehensive approach is required in managing these patients, including treatment of comorbidities such as cataracts and psychological reassurance.

Keyword

Quality of life; Wet age-related macular degeneration

MeSH Terms

Cataract
Color Vision
Comorbidity
Dependency (Psychology)
Humans
Hypertension
Macular Degeneration
National Eye Institute (U.S.)
Ophthalmology
Quality of Life
Surveys and Questionnaires
Vision, Ocular
Visual Acuity

Reference

1. Klein R, Klein BE, Linton KL. Prevalence of age-related maculopathy. The Beaver Dam Eye Study. Ophthalmology. 1992. 99:933–943.
2. Friedman DS, O'Colmain BJ, Muñoz B, et al. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol. 2004. 122:564–572.
3. Ferris FL 3rd, Fine SL, Hyman L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol. 1984. 102:1640–1642.
4. Kang S, Cho WK, Roh YJ. The efficacy of ranibizumab for choroidal neovascularization in age-related macular degeneration. J Korean Ophthalmol Soc. 2009. 50:725–730.
5. Lee HJ, Park JY, Ohn YH. Electrophysiological and morphological changes after intravitreal bevacizumab injection with macular edema or choroidal neovascularization. J Korean Ophthalmol Soc. 2009. 50:1824–1830.
6. Cho SW, Bae JH, Song SJ. Anatomical non-responder to intravitreal bevacizumab for neovascular age-related macular degeneration. J Korean Ophthalmol Soc. 2010. 51:1464–1470.
7. Cahill MT, Banks AD, Stinnett SS, Toth CA. Vision-related quality of life in patients with bilateral severe age-related macular degeneration. Ophthalmology. 2005. 112:152–158.
8. Mangione CM, Gutierrez PR, Lowe G, et al. Influence of age-related maculopathy on visual functioning and health-related quality of life. Am J Ophthalmol. 1999. 128:45–53.
9. DeCarlo DK, Scilley K, Wells J, Owsley C. Driving habits and health-related quality of life in patients with age-related maculopathy. Optom Vis Sci. 2003. 80:207–213.
10. Chylack LT Jr, Wolfe JK, Singer DM, et al. The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group. Arch Ophthalmol. 1993. 111:831–836.
11. Lee P, Minckler D. The importance of "quality of care". Ophthalmology. 1996. 103:549–550.
12. Williams RA, Brody BL, Thomas RG, et al. The psychosocial impact of macular degeneration. Arch Ophthalmol. 1998. 116:514–520.
13. Brody BL, Gamst AC, Williams RA, et al. Depression, visual acuity, comorbidity, and disability associated with age-related macular degeneration. Ophthalmology. 2001. 108:1893–1900.
14. Mangione CM, Lee PP, Pitts J, et al. Psychometric Properties of the National Eye Institute Visual Function Questionnaire (NEI-VFQ). NEI-VFQ field test investigators. Arch Ophthalmol. 1998. 116:1496–1504.
15. Mangione CM, Lee PP, Gutierrez PR, et al. Development of the 25-item National Eye Institute Visual Function Questionnaire. Arch Ophthalmol. 2001. 119:1050–1058.
16. Clemons TE, Chew EY, Bressler SB, McBee W. National Eye Institute Visual Function Questionnaire in the Age-Related Eye Disease Study (AREDS): AREDS Report No. 10. Arch Ophthalmol. 2003. 121:211–217.
17. Revicki DA, Rentz AM, Harnam N, et al. Reliability and validity of the National Eye Institute Visual Function Questionnaire-25 in patients with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2010. 51:712–717.
18. Chia EM, Mitchell P, Ojaimi E, et al. Assessment of vision-related quality of life in an older population subsample: The Blue Mountains Eye Study. Ophthalmic Epidemiol. 2006. 13:371–377.
19. Hogg RE, Woodside JV, Gilchrist SE, et al. Cardiovascular disease and hypertension are strong risk factors for choroidal neovascularization. Ophthalmology. 2008. 115:1046–1052.
20. Williams RA, Brody BL, Thomas RG, et al. The psychosocial impact of macular degeneration. Arch Ophthalmol. 1998. 116:514–520.
21. Mangione CM, Berry S, Spritzer K, et al. Identifying the content area for the 51-item National Eye Institute Visual Function Questionnaire: results from focus groups with visually impaired persons. Arch Ophthalmol. 1998. 116:227–233.
22. Rovner BW, Casten RJ. Activity loss and depression in age-related macular degeneration. Am J Geriatr Psychiatry. 2002. 10:305–310.
23. Mitchell J, Bradley P, Anderson SJ, et al. Perceived quality of health care in macular disease: a survey of members of the Macular Disease Society. Br J Ophthalmol. 2002. 86:777–781.
Full Text Links
  • JKOS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr