J Korean Pediatr Soc.  2003 Feb;46(2):195-197.

Familial Sick Sinus Syndrome

• Nam IH
• Cheon SH
• Kil HR

Abstract

Sick sinus syndrome(SSS) constitutes a spectrum of cardiac arrhythmia, including sinus bradycardia, sinus pause-arrest, sinoatrial block, slow escape rhythm, bradyarrhythmia and tachyarrhythmia. SSS is relatively uncommon in children but its exact incidence is unknown because diagnostic criteria are not uniform and most children with SSS, in general are asymptomatic. SSS may be primary(organic sinus node disease) or secondary(cardiac surgery comprises much of SSS in children and adolescents), but it can hardly be caused by familial relations as well. We reports an occurrence of familial sick sinus syndrome. Mother was diagnosed as SSS, which was presented by symptoms of dizziness and treated by permanent pacemaker(DDD). Also, two daughters revealed SSS with non- compacted cardiomyopathy on neonatal screening and fetal echocardiography respectively. We concluded that familial SSS may occur, so familial screening should be suggested.

Keyword

Sick sinus syndrome; Cardiomyopathy

MeSH Terms

Arrhythmias, Cardiac
Bradycardia
Cardiomyopathies
Child
Dizziness
Echocardiography
Humans
Incidence
Infant, Newborn
Mass Screening
Mothers
Neonatal Screening
Nuclear Family
Sick Sinus Syndrome*
Sinoatrial Block
Sinoatrial Node
Tachycardia
United Nations