J Korean Soc Coloproctol.  2009 Aug;25(4):259-263.

Plexiform Neurofibroma Involving the Ascending Colonic Mesentery in Neurofibromatosis Type I

• Park SJ
• Choi SI
• Lee SH
• Lee KY

Abstract

We report a rare case of plexiform neurofibroma involving the ascending colonic mesentery in von Recklinghausen disease. A 20-yr-old male with neurofibromatosis type I was admitted because of abdominal pain, nausea, and vomiting. On physical examination, there were multiple cafe-au-lait spots over the patient's entire body. An abdominal computed tomography scan showed a hypodense mass in the ascending colonic mesentery. He underwent a laparoscopic right hemicolectomy with complete excision of the mass. The histological examination showed that the mass consisted of wavy, long-spindled cells, and the immunohistochemical stain for S-100 protein confirmed the mass to be a neurofibroma of the mesentery. The patient had an uneventful postoperative course and no signs of recurrence 16 mo after operation.

Keyword

von Recklinghausen disease; Plexiform neurofibroma; Mesentery

MeSH Terms

Abdominal Pain
Cafe-au-Lait Spots
Colon, Ascending
Humans
Male
Mesentery
Nausea
Neurofibroma
Neurofibroma, Plexiform
Neurofibromatoses
Neurofibromatosis 1
Physical Examination
Recurrence
S100 Proteins
Vomiting
Cafe-au-Lait Spots
S100 Proteins