J Korean Soc Coloproctol.
2000 Oct;16(5):339-345.
Four Cases of HNPCC Including Two Cases with Synchronous Stomach Cancer
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Kosin University, Busan, Korea.
- 2Department of General Surgery, College of Medicine, Kosin University, Busan, Korea.
Abstract
- Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant disease characterized by early manifestation of colorectal cancer (CRC), occurrence of multiple colorectal tumors and high frequencies of extracolonic malignancies. Evaluation of clinical findings in concert with a well-documented and extended pedigree and genetic studies of colorectal cancer can identify person who are at high risk and who thereby might benefit from targeted early detection and primary prevention programs. Here we report 4 cases of HNPCC including 2 cases with synchronous gastric cancers.
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