J Korean Burn Soc.  2014 Jun;17(1):20-24.

Plasma Lactate and Base Deficit: Early Predictors of Morbidity in Burn Patients

• Ha CM
• Ahn HY
• Cho IS
• Jung YM
• Choi SY
• Pyo CH

Abstract

PURPOSE
Plasma lactate and base deficit has been used as a marker to determine the status of tissue perfusion in trauma and clinically ill patients and also to predict the outcome of these patients. This study was performed to investigate the effect of plasma lactate and base deficit in predicting burn patients outcome.
METHODS
A retrospective review was performed on 102 patients from January 2012 to December 2013 who were admitted as severe burn patients to our burn care unit. Plasma lactate and base deficit were measured upon admission to the hospital and SIRS score, hospital day, ABSI and TBSA were collected after admission.
RESULTS
102 patients were enrolled. Initial base deficit, hospital day, burn surface area and ABSI score showed statistical differences between low SIRS group and high SIRS group. The SIRS score, hospital day and ABSI score showed statistical differences between high base deficit group and low base deficit group (P<0.05). But there were no statistical differences in plasma lactate between two groups (P>0.05).
CONCLUSION
In this study, initial base deficit but not plasma lactate, was predictor of morbidity following burn injury.

Keyword

Burn; Plasma lactate; Base deficit; SIRS

MeSH Terms

Burns*
Humans
Lactic Acid*
Perfusion
Plasma*
Retrospective Studies
Lactic Acid