J Korean Soc Pediatr Nephrol.  2009 Oct;13(2):242-247.

A Case of Diabetic Nephropathy Progressed to End-Stage Renal Disease in an Adolescent with Type 1 Diabetes

• Yoon JE
• Kwon SK
• Ha TS

Abstract

Type 1 diabetes mellitus (T1DM) commonly occurs in childhood and adolescence and diabetic nephropathy is a serious metabolic complication of T1DM that leads to serious morbidity. With poor glycemic control prepubertal diabetes duration contributes to the risk of long-term microvascular complications, however, the younger age at onset or longer prepubertal diabetes duration seems to prolong the time to development of microalbuminuria or later end-stage renal disease (ESRD). Therefore, there have been a few cases of diabetic nephropathy in prepubertal patients and therefore the ESRD cases developed during adolescence in T1DM children were very rare. Here we report an adolescent with T1DM who had poor glycemic control and was diagnosed as diabetic nephropathy in a prepubertal period and leading to end-stage renal disease during adolescence.

Keyword

Diabetic nephropathy; Type 1 diabetes mellitus; End-stage renal disease; Adolescence

MeSH Terms

Adolescent
Child
Diabetes Mellitus
Diabetes Mellitus, Type 1
Diabetic Nephropathies
Humans
Kidney Failure, Chronic