J Korean Soc Pediatr Endocrinol.  2002 Dec;7(2):215-220.

Follow-up Study of Hyperthyrotropinemia Detected by Neonatal Screening Test

• Paik KH
• Kim SH
• Jin DK

Abstract

PURPOSE: To understand natural course of transient hyperthyrotropinemia, so that the unnecessary treatment could be avoided.
METHODS
Total 182 healthy newborns whose TSH levels in newborn screening test had been higher than 20 microIU/mL were recalled. Their serum levels of TSH, T4, free T4 were checked.
RESULTS
Among 182 newborns, 10 newborns had congenital hypothyroidism. 68.1 % of healthy newborns who had high TSH levels were normalized within 2 months and all of the rests were normalized within 5 months.
CONCLUSION
Transient hyperthyrotropinemia in newborns improves spontaneously. The unnecessary treatment of transient hyperthyrotropinemia should be avoided.

Keyword

TSH; Hyperthyrotropinemia; Congenital hypothyroidism

MeSH Terms

Congenital Hypothyroidism
Follow-Up Studies*
Humans
Infant, Newborn
Mass Screening
Neonatal Screening*