Pediatr Gastroenterol Hepatol Nutr.  2014 Jun;17(2):116-120.

Two Cases of Infantile Intra-abdominal Inflammatory Myofibroblastic Tumor

  • 1Division of Pediatric Surgery, Department of Surgery, Pusan National University Children's Hospital, Pusan National University School of Medicine, Yangsan, Korea.


Inflammatory myofibroblastic tumor (IMT) is rare mesenchymal solid tumor that consists of proliferating myofibroblasts with an inflammatory infiltrate background. It has a very low prevalence in infants and occurs mainly in children and young adults. IMT are mainly located in the thoracic cavity, but intra-abdominal lesions are rare. IMT can exhibit locally aggressive neoplastic processes and metastases similar to malignancies, so, have clinical importance. Herein, we describe two infantile intra-abdominal IMT cases presenting with incidentally found palpable abdominal mass. A 4-month-old male infant had IMT at the ileal mesentery and a 5-month-old male infant had IMT at liver. Both cases were successfully treated by complete surgical resection without complication or recurrence. Considering the biological behavior of the intermediate type of neoplasm in IMT, we expect good survivals when achieving appropriate surgical resection without adjuvant therapy in infantile intra-abdominal IMT.


Inflammatory myofibroblastic tumor; Intraabdominal; Infant

MeSH Terms

Neoplasm Metastasis
Neoplastic Processes
Thoracic Cavity
Young Adult


  • Fig. 1 Computed tomography scan. A cyst-like mass attached to small intestine and located at right abdomen, inferior to liver and anterior to kidney.

  • Fig. 2 Resected mass from mesentery of ileum.

  • Fig. 3 Pathologic findings. (A) Spindle myofibroblastic cells in a fibromyxoid background with intermingled inflammatory cells (H&E, ×200). (B) Tumor cells highlighted by ALK (×400). (C) Tumor cells highlighted by SMA (×400).

  • Fig. 4 Magnetic resonance images. (A) T1 weighted image showing a large mass at right liver lobe with low signal intensities. (B) T2 weighted image showing a mass with heterogenous signal intensities along with central high and focal intermediate signal intensities.

  • Fig. 5 Intraoperative findings. Large mass at right lobe of liver.


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