Obstet Gynecol Sci.  2014 Jan;57(1):82-85.

Successful pregnancy by direct intraperitoneal insemination in an infertile patient with failure of recanalization of isthmic stenosis after laparoscopic radical trachelectomy

Affiliations
  • 1Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. chnkim@amc.seoul.kr

Abstract

Radical trachelectomy is a promising fertility-sparing treatment for patients with early stage cervical cancer who want to preserve their fertility. However, isthmic stenosis occurs frequently in patients who received radical trachelectomy and it is one of the causes of infertility following radical trachelectomy. Moreover, despite the treatment for recanalization of isthmic stenosis, recanalization can fail or isthmic stenosis can recur. Herein we report a successful pregnancy and birth by direct intraperitoneal insemination in an infertile woman with failure of recanalization of isthmic stenosis after laparoscopic radical trachelectomy.

Keyword

Direct intraperitoneal insemination; Isthmic stenosis; Laparoscopic radical trachelectomy

MeSH Terms

Constriction, Pathologic*
Female
Fertility
Humans
Infertility
Insemination*
Parturition
Pregnancy*
Uterine Cervical Neoplasms

Figure

  • Fig. 1 (A) Magnetic resonance imaging shows 1.6 cm-sized mass in anterior wall of the cervix (white arrow indicates the cervical mass). (B) Gross finding shows the tumor confirmed as poorly differentiated squamous cell carcinoma with clear resection margin (measuring 3.3 × 3.0 × 0.5 cm) (white arrow indicates the cervical mass).

  • Fig. 2 The needle attached to semen containing syringe was put into the posterior cul-de-sac along the biopsy guide.


Reference

1. Shepherd JH, Spencer C, Herod J, Ind TE. Radical vaginal trachelectomy as a fertility-sparing procedure in women with early-stage cervical cancer-cumulative pregnancy rate in a series of 123 women. BJOG. 2006; 113:719–724.
2. Boss EA, van Golde RJ, Beerendonk CC, Massuger LF. Pregnancy after radical trachelectomy: a real option? Gynecol Oncol. 2005; 99:S152–S156.
3. Seli E, Tangir J. Fertility preservation options for female patients with malignancies. Curr Opin Obstet Gynecol. 2005; 17:299–308.
4. Plante M. Fertility preservation in the management of gynecologic cancers. Curr Opin Oncol. 2000; 12:497–507.
5. Bernardini M, Barrett J, Seaward G, Covens A. Pregnancy outcomes in patients after radical trachelectomy. Am J Obstet Gynecol. 2003; 189:1378–1382.
6. Kato O, Takatsuka R, Asch RH. Transvaginal-transmyometrial embryo transfer: the Towako method; experiences of 104 cases. Fertil Steril. 1993; 59:51–53.
7. Aust TR, Herod JJ, Gazvani R. Placement of a Malecot catheter to enable embryo transfer after radical trachelectomy. Fertil Steril. 2005; 83:1842.
8. Ben Rhouma K, Ben Miled E, Ben Marzouk A, Rihani M, Bakir M. Direct intraperitoneal insemination and controlled ovarian hyperstimulation in subfertile couples. J Assist Reprod Genet. 1994; 11:189–192.
9. Misao R, Itoh M, Nakanishi Y, Tamaya T. Direct intraperitoneal insemination in ovarian hyperstimulation cycles induced with gonadotropin-releasing hormone agonist. Clin Exp Obstet Gynecol. 1997; 24:133–134.
10. Tiemessen CH, Bots RS, Peeters MF, Evers JL. Direct intraperitoneal insemination compared to intrauterine insemination in superovulated cycles: a randomized cross-over study. Gynecol Obstet Invest. 1997; 44:149–152.
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