Korean J Neurogastroenterol Motil.
2006 Dec;12(2):122-126.
The Significance of Mucosal 'Whitish Discoloration' in the Second Portion of Duodenum: From a Gastric Functional Point of View
- Affiliations
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- 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. hjpark21@yumc.yonsei.ac.kr
- 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
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BACKGROUND/AIMS: A mucosal 'whitish discoloration' of the duodenal second portion may be discorvered during esophago-gastroduodenoscopy (EGD). This study investigated the gastric functional implication and histological abnormalities of mucosal 'whitish discoloration'.
METHODS
The upper gastrointestinal symptoms, gastric emptying time and histology findings were compared in patients with functional dyspepsia (FD) showing mucosal 'whitish discoloration' of the duodenal second portion (group I), FD patients without 'whitish discoloration' (group II), and normal controls who have neither symptoms nor 'whitish discoloration' (normal controls).
RESULTS
There was a significant difference between group I (147.6 min) and group II (99.6 min) or normal controls (75.8 min). However there was no difference between group II and normal controls. There was no histological difference in the three groups. In particular, there was no mucosal infiltration of macrophage in second portion of duodenum.
CONCLUSIONS
Mucosal 'whitish discoloration' of the duodenal second portion, uncommon occurrence in EGD, can be correlated with a delayed gastric emptying time.
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