Korean J Med.  2008 Apr;74(4):435-440.

A case of primary malignant uterine cervical Non-Hodgkin's lymphoma with breast involvement

Affiliations
  • 1Department of Internal Medicine, Eulji University School of Medicine, Daejon, Korea. lee982023@eulji.ac.kr
  • 2Department of Radiology, Eulji University School of Medicine, Daejon, Korea.
  • 3Department of Anatomic Pathology, Eulji University School of Medicine, Daejon, Korea.
  • 4Department of Clinical Pathology, Eulji University School of Medicine, Daejon, Korea.

Abstract

Primary lymphoma arising from the uterine cervix has been rarely encountered, and breast involvement is rare because of the relative paucity of lymphoid tissue in the breast. A 32-year-old woman with a primary malignant lymphoma of the uterine cervix and breast involvement is reported. The patient presented with post-coital vaginal bleeding, and punch biopsy of the cervix revealed the diffuse large B cell type of malignant lymphoma. PET-scan was done for staging, and abnormal FDP uptakes were detected in a uterine cervical mass and breast nodule. Ultrasonography-guided needle biopsy was done for the breast mass, and 2 biopsied nodules revealed fibroadenoma and diffuse large B cell lymphoma. The patient (Ann Arbor stage IV) was treated with 6 cycles of combination chemotherapy with CHOP plus rituximab. The patient went into complete remission. Thereafter, 4500cGy pelvic irradiation was done for adjuvant therapy.

Keyword

Primary uterine cervical lymphoma; Breast involvement

MeSH Terms

Adult
Antibodies, Monoclonal, Murine-Derived
Biopsy
Biopsy, Needle
Breast
Cervix Uteri
Drug Therapy, Combination
Female
Fibroadenoma
Formycins
Humans
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell
Lymphoma, Non-Hodgkin
Ribonucleotides
Uterine Hemorrhage
Rituximab
Antibodies, Monoclonal, Murine-Derived
Formycins
Ribonucleotides
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