Korean J Gastroenterol.
1999 Jul;34(1):131-135.
Malignant Fibrous Histiocytoma of the Liver with Cystic Change
Abstract
- Malignant fibrous histiocytoma (MFH) of the liver is very rare. We report a case of MFH of the liver with cystic change. A 56-year-old woman was admitted with abdominal pain on right upper quadrant and fever. Liver function tests showed nomal profiles and the concentrations of alpha fetoprotein (alphaFP), carcinoembrionic antigen (CEA) and CA 19-9 were 1.46 ng/mL, 4.53 ng/mL and 350 ng/mL, respectively. An abdominal computed tomography disclosed a 8.7 x 7.4 cm sized cystic mass with multiple internal septa in the left lobe of the liver. Histological examination of the resected tumor showed large pleomorphic cells, spindle cells with interspersed myxoid material, and occasional giant cells. Immunohistochemically, tumor cells were strongly positive for vimentin and alpha 1-antitrypsin, but negative for cytokeratin and epithelial membrane antigen. The myxoid material was positive for alcian blue-PAS stain.
