Korean J Dermatol.
1998 Aug;36(4):683-687.
A Case of Mycosis Fungoides Treated with Retinoid and PUVA
- Affiliations
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- 1Department of Dermatology, College of Medicine, Keimyung Unviersity, Taegu, Korea.
Abstract
- A 38-year-old woman showed pruritic reddish patches, plaques and an indurated mass of 6 year's duration on the face, trunk, back, upper and lower extremities. Histopathological and immunohistochemical findings suggested the diagnosis of mycosis fungoides (tumor stage). She was treated with chemotherapy(CVP regimen) with a mild resolution. Then 6 months later, a skin lesion on the forehead developed in to a tumorous lesion and the truncal lesions got worse. So we tried combination therapy with Retinoid(etretinate 0.5mg/kg/day) and PUVA (Total dose of 228 joules/cm(2)) for 7 months. After 7 months, marked improvement of the skin lesions was noticed. The combination of Retinoid and PUVA was considered a good therapeutic trial for mycosis fungoides of the early advanced stage.
