Korean J Dermatol.  2002 Nov;40(11):1389-1392.

A Case of Piebaldism Treated by Combination Therapy with Suction Blister Epidermal Graft and the Alexandrite Laser

• Choe HC
• Kim MY
• Park HJ
• Byun DG
• Park CJ

Abstract

Piebaldism is a rare, autosomal dominant inherited disorder, characterized by inborn hypopigmented skin and hair. It is characterized by stable leukoderma with white forelock and vitiligo like amelanotic macules usually containing hyperpigmented macules at the periphery. As the leukodermic lesions in piebaldism are unresponsive to any form of topical or systemic medical treatment, several methods for autologous transplantation of melanocytes and epidermal transplantation methods have been developed and there are no specific treatment methods for hyperpigmented patch in piebaldism. A 12-year-old female had piebaldism from birth. Suction blister epidermal graft was tried at hypopigmented patches on the posterior aspects of both lower legs and the Q-switched Alexandrite laser was used at the site of the hyperpigmented patches. Combination therapy with suction blister epidermal graft and a Q-switched Alexandrite laser on piebaldism may be effective method.

Keyword

Piebaldism; Alexandrite laser; Suction blister epidermal transplantation

MeSH Terms

Autografts
Blister*
Child
Female
Hair
Humans
Lasers, Solid-State*
Leg
Melanocytes
Parturition
Piebaldism*
Skin
Suction*
Transplantation, Autologous
Transplants*
Vitiligo