Korean J Dermatol.
2004 Feb;42(2):208-210.
A Case of SAPHO Syndrome
- Affiliations
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- 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. holyderma@catholic.ac.kr
- 2Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- 3Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
- The term, SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is an acronym to designate a clinico-radiologic entity with combination of skin, bone, and joint manifestations. We, herein, present a case of SAPHO syndrome in a 27-year-old man with pruritic, localized, crops of deep-seated pustules on both palms and soles for 2 years, and multiple joints pain including anterior upper chest pain for 3 years. Histopathologically, the palm showed a large intraepidermal cavity filled with many neutrophils, and many typical spongiform pustules at the wall of it. Radiographically, the left sternoclavicular joint showed synovitis, osteitis and hyperostosis.
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