Korean J Dermatol.  2007 May;45(5):458-461.

A Case of Secondary Cutaneous Diffuse Large B-cell Lymphoma

  • 1Department of Dermatology, College of Medicine, Hallym University, Anyang, Korea. kkj51818@hallym.or.kr


Cutaneous, diffuse, large B-cell lymphoma (DLBCL) is characterized by a diffuse dermal infiltration which is composed of large centroblasts and immunoblasts. It is subdivided into a primary form arising from the skin and a secondary form which is metastasized from the lymph node. Secondary DLBCL has a more aggressive clinical course than the primary form. We report a 39-year-old female patient who presented with a 2 cm sized, erythematous, subcutaneous nodule on her left upper arm. She had been treated for brain-diffuse, large B-cell lymphoma which occurred 5 years before. The histopathologic and immunohistochemical examinations of the skin lesion also showed diffuse, large, B-cell lymphoma.


Secondary cutaneous diffuse large B-cell lymphoma
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