Korean J Urol.  2004 Dec;45(12):1288-1291.

Hybrid Squamous-Verrucous Carcinoma of Penis

Affiliations
  • 1Departments of Urology, College of Medicine, Inje University, Seoul, Korea. stonemt@medimail.co.kr
  • 2Departments of Pathology, College of Medicine, Inje University, Seoul, Korea.

Abstract

We report a rare case of hybrid squamous-verrucous carcinoma of penis that grew extensively in the glans and prepuce of a 68-year-old man. He presented himself with penile discharge and pain upon voiding. The penile glans and prepuce were eroded and replaced by a large, fungating, cauliflower-like ulcerative mass. There was no inguinal or pelvic lymph node enlargement. Partial penectomy was done and histologically, the superficial spreading type, well differentiated squamous cell carcinoma was seen with only minimal invasion of the background verrucous carcinoma with a pushing margin. There were no complications and recurrence of the tumor at 12 months after partial penectomy.

Keyword

Penis; Carcinoma, verrucous; Carcinoma squamous cell; Hybrid

MeSH Terms

Aged
Carcinoma, Squamous Cell
Carcinoma, Verrucous
Cytochrome P-450 CYP1A1
Humans
Lymph Nodes
Male
Penis*
Recurrence
Ulcer
Cytochrome P-450 CYP1A1
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