Changes in Serum Electrolyte Following Transurethral Resection of the Prostate When 1.5% Glycine Solution and 5% Dextrose-Water Solution are Used as Irrigants

Lee, Gil Ho; Kim, Je Jong; Koh, Sung Kun

Abstract

Transurethral resection syndrome are caused by the sudden intravascular absorption of large volumes of the irrigating solution which are used during transurethral surgery. It relates to many determining conditions of the patient postoperatively. We studied changes in serum electrolyte following transurethral resection of prostate in 61 patients used 5% Dextrose-Water solution as the irrigant and 46 patients used 1.5% glycine as the irrigant of benign prostatic hypertrophy. We divided the patients into group I and II. group I : those were given 5% Dextrose-Water solution as the irrigant. group II : those were given 1.5% glycine as the irrigant. Change in serum ammonia was obtained in 19 patients of group II. Following results were obtained. 1. Operation time, resected weight and amount of irrigant between group I and II showed no difference, statistically. 2. Serum sodium concentration was decreased in 42 cases of group I (range : 1-20mEq/L, mean : 5.0mEq/L). 3. Serum sodium concentration was decreased in 31 cases of group II (range : 1-18mEq/L, mean : 6.0mEq/L). These changes in serum concentration between group I and group II showed no significant difference, statistically. 4. Change in serum sodium concentration in the group I showed no significant correlation with operation time, resected weight and amount of irrigation. 5. Change in serum sodium concentration in the group II showed no significant correlation with operation time, resected weight and amount of irrigation. 6. Serum ammonia concentration was increased in 10 patients of 19 patients in group II (range : 5-100ug/dl, mean : 42ug/dl).