Korean J Thorac Cardiovasc Surg.  2006 Apr;39(4):323-327.

Contralateral Single Lung Re-transplantation in the Patient with Lymphangioleiomyomatosis due to Graft Failure

• Joung EK
• Paik HC
• Hwang JJ
• Kim JH
• Youn YN
• Lee DY

Abstract

Lymphangioleiomyomatosis (LAM) is a rare disease in women of childbearing ages that eventually leads to respiratory failure. Lung transplantation is the only conclusive therapeutic modality in end-stage LAM. While single-lung transplantation is the preferred operation, the graft failure or recurrence of LAM was reported. We performed a single lung transplantation on a 36-year-old woman suffering from respiratory failure due to lymphangioleiomyomatosis. After a 1-year follow up, the patient was readmitted because of graft failure with collapsed transplanted lung. The lung volume reduction surgery (LVRS), tracheostomy and ventilator care were performed. However, neither the medical nor surgical treatment had any effect. Subsequently, we performed a contralateral single lung re-transplantation and had a good postoperative results.

Keyword

Lung transplantation; Reoperation; Lymphangioleiomyomatosis

MeSH Terms

Adult
Female
Follow-Up Studies
Humans
Lung Transplantation
Lung*
Lymphangioleiomyomatosis*
Pneumonectomy
Rare Diseases
Recurrence
Reoperation
Respiratory Insufficiency
Tracheostomy
Transplants*
Ventilators, Mechanical