Infect Chemother.  2013 Jun;45(2):230-233. 10.3947/ic.2013.45.2.230.

Detection of an Infected N-butyl-2-cyanoacrylate Plug by F-18 FDG PET/CT Scan in a Patient Who Received Endoscopic Intervention for Gastric Variceal Bleeding

Affiliations
  • 1Department of Internal Medicine, Inha University Hospital, Incheon, Korea. ljinsoo@inha.ac.kr
  • 2Department of Nuclear Medicine, Inha University Hospital, Incheon, Korea.

Abstract

Injection of N-butyl-2-cyanoacrylate has been used successfully for treatment of gastric variceal bleeding. Bacteremia after injection of N-butyl-2-cyanoacrylate is well known, however, the method for diagnosis of infected endovascular injected material has remained uncertain. This is the first case reporting use of F-18 FDG PET/CT in detection of the source of infection after control of endoscopic bleeding with N-butyl-2-cyanoacrylate.

Keyword

Bacteremia; Septic thrombophlebitis; FDG; PET/CT; N-butyl-2-cyanoacrylate

MeSH Terms

Bacteremia
Enbucrilate
Hemorrhage
Humans
Enbucrilate

Figure

  • Figure 1 Abdominal CT (A) and gastroscopy (B) show a remnant N-butyl-2-cyanoacrylate plug protruding into the cardia.

  • Figure 2 Focal FDG uptake around the N-butyl-2-cyanoacrylate plug in the stomach cardia is visible on fusion transverse images of FDG PET/CT.

  • Figure 3 Follow up FDG PET/CT after two weeks of treatment shows markedly decreased FDG uptake around the N-butyl-2-cyanoacrylate plug on fusion transverse images.


Reference

1. Sarin SK. Long-term follow-up of gastric variceal sclerotherapy: an eleven-year experience. Gastrointest Endosc. 1997. 46:8–14.
Article
2. Ho H, Zuckerman MJ, Wassem C. A prospective controlled study of the risk of bacteremia in emergency sclerotherapy of esophageal varices. Gastroenterology. 1991. 101:1642–1648.
Article
3. Camara DS, Gruber M, Barde CJ, Montes M, Caruana JA Jr, Chung RS. Transient bacteremia following endoscopic injection sclerotherapy of esophageal varices. Arch Intern Med. 1983. 143:1350–1352.
Article
4. Cohen LB, Korsten MA, Scherl EJ, Velez ME, Fisse RD, Arons EJ. Bacteremia after endoscopic injection sclerosis. Gastrointest Endosc. 1983. 29:198–200.
Article
5. Quinn J, Wells G, Sutcliffe T, Jarmuske M, Maw J, Stiell I, Johns P. Tissue Tissue adhesive versus suture wound repair at 1 year: randomized clinical trial correlating early, 3-month, and 1-year cosmetic outcome. Ann Emerg Med. 1998. 32:645–649.
Article
6. Brayko CM, Kozarek RA, Sanowski RA, Testa AW. Bacteremia during esophageal variceal sclerotherapy: its cause and prevention. Gastrointest Endosc. 1985. 31:10–12.
Article
7. Liao SC, Ko CW, Yeh HZ, Chang CS, Yang SS, Chen GH. Successful treatment of persistent bacteremia after endoscopic injection of N-butyl-2-cyanoacrylate for gastric varices bleeding. Endoscopy. 2007. 39:Suppl 1. E176–E177.
Article
8. Wahl P, Lammer F, Conen D, Schlumpf R, Rock A. Septic complications after injection of N-butyl-2-cyanoacrylate: report of two cases and review. Gastrointest Endosc. 2004. 59:911–916.
Article
9. Blockmans D, Knockaert D, Maes A, De Caestecker J, Stroobants S, Bobbaers H, Mortelmans L. Clinical value of [(18)F]fluoro-deoxyglucose positron emission tomography for patients with fever of unknown origin. Clin Infect Dis. 2001. 32:191–196.
Article
10. Stumpe KD, Dazzi H, Schaffner A, von Schulthess GK. Infection imaging using whole-body FDG-PET. Eur J Nucl Med. 2000. 27:822–832.
Article
11. Güngör T, Engel-Bicik I, Eich G, Willi UV, Nadal D, Hossle JP, Seger RA, Steinert HC. Diagnostic and therapeutic impact of whole body positron emission tomography using fluorine-18-fluoro-2-deoxy-D-glucose in children with chronic granulomatous disease. Arch Dis Child. 2001. 85:341–345.
Article
12. Basu S, Chryssikos T, Moghadam-Kia S, Zhuang H, Torigian DA, Alavi A. Positron emission tomography as a diagnostic tool in infection: present role and future possibilities. Semin Nucl Med. 2009. 39:36–51.
Article
Full Text Links
  • IC
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr