Korean J Otolaryngol-Head Neck Surg.  2007 Apr;50(4):362-365.

A Case of Granulocytic Sarcoma Presenting as a Head and Neck Neoplasm

Affiliations
  • 1Department of Otolaryngology-Head & Neck Surgery, College of Medicine, Pochon CHA University, Seongnam, Korea. yoochankee@empal.com
  • 2Department of Pathology, College of Medicine, Pochon CHA University, Seongnam, Korea.

Abstract

The granulocytic sarcoma is a rare tumor and occurs primarily in patients with acute myelogenous leukemia (AML). The granulocytic sarcoma can arise before, concurrent with, or following acute myeloid leukemia. This tumor can be rarely represented as the initial presentation of acute myeloid leukemia without any signs or symptoms of leukemia. Granulocytic sarcoma, rarely, can also occur in unexpected regions, including the head and neck. This tumor is very often misdiagnosed as a malignant lymphoma which leads to inappropriate treatment and poor outcome. Therefore, clinical, histopathological and immumohistochemical findings should be evaluated before any diagnosis of malignant lymphoma. We report, with a brief review of literature, a case of granulocytic sarcoma presenting as a head and neck neoplasm.

Keyword

Sarcoma, granulocytic; Head and neck neoplasm

MeSH Terms

Diagnosis
Head*
Humans
Leukemia
Leukemia, Myeloid, Acute
Lymphoma
Neck*
Sarcoma, Myeloid*
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