Korean J Otolaryngol-Head Neck Surg.  2004 Nov;47(11):1178-1180.

A Case of Castleman's Disease Presenting as an Isolated Hypervascular Tumor in Neck

• Son EJ
• Lee YJ
• Koo JS
• Choi HS

Abstract

Castleman's disease is an unusual condition of lymphoproliferation, still a rarer cause of isolated neck mass. Also known as angiofollicular lymph node hyperplasia, it is a pathological diagnosis, with three histologic variants (hyaline vascular, plasma-cell, and mixed) and two clinical types (localized and multicentric). We present a case of an isolated neck mass of long standing, which was treated by surgical excision and histopathologically confirmed as hyaline vascular type of Castleman's disease. The lesion showed distinct hypervascular features on imaging studies. Castleman's disease should be considered as a differential diagnosis in isolated hypervascular neck masses.

Keyword

Castleman's disease; Neck mass

MeSH Terms

Diagnosis
Diagnosis, Differential
Giant Lymph Node Hyperplasia*
Hyalin
Neck*