Korean J Obstet Gynecol.  2005 Sep;48(9):2067-2072.

Evaluation of prevention program for neonatal vertical transmission from HBsAg positive mother in Korea

Affiliations
  • 1Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. kyungseo@yumc.yonsei.ac.kr
  • 2Vaccine Preventable Disease Control and National Immunization Program Division, Korea Center for Disease Control and Prevention (KCDC), Korea.
  • 3Infectious Disease Surveillance Division, Korea Center for Disease Control and Prevention (KCDC), Korea.

Abstract


OBJECTIVE
For evaluation of prevention program for neonatal vertical transmission from HBsAg positive mother in Korea
METHODS
From January 15th to February 15th 2003, the status of neonatal vaccination, immunoglobuline injection and breast feeding of HBsAg positive mother was evaluated by using mailed questionnaire in 848 hostpitals with more than 100 deliveries in the year of 2001. 341 out of 848 (40.2%) hospitals returned questionnaires.
RESULTS
91.9% of total hospital reported that the vaccination of hepatitis B and immunoglobulin injection was done within 12 hours after birth in more than 90% of neonate. The most commonly used vaccine type was 0-1-6 method. In case of unknown result of HBsAg/ HBsAb in mother, 84.4% of hospitals delayed immunoglobulin injection until complete report, however 63% of hospitals gave hepatitis vaccine without delay before complete result. The breast feeding of HBsAg positive mother was recommended according to the result of HBeAg in 66.3% of hospitals while 24.9% of hospitals recommend breast feeding.
CONCLUSION
Most hospitals in Korea reported that vaccination of Hepatitis B and immunoglobulin injection was done within 12 hours after in over 90% of neonate whose mother was HBsAg Positive. But continuous education and careful monitoring are required for injection method and vaccination policy in neonates of mothers with unknown result of HBsAg/HBsAb of mother.

Keyword

Vertical transmission; HBsAg positive mother; Neonatal immunization; Breast feeding

MeSH Terms

Breast Feeding
Education
Hepatitis
Hepatitis B
Hepatitis B e Antigens
Hepatitis B Surface Antigens*
Humans
Immunoglobulins
Infant, Newborn
Korea*
Mothers*
Parturition
Postal Service
Surveys and Questionnaire
Vaccination
Hepatitis B Surface Antigens
Hepatitis B e Antigens
Immunoglobulins
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