Cancer Res Treat.  2006 Apr;38(2):118-120.

A Case of Recurrent Solid Pseudopapillary Tumor of the Pancreas with Involvement of the Spleen and Kidney

• Park SE
• Park NS
• Chun JM
• Park NW
• Yang YJ
• Yun GW
• Lee HJ
• Yun HJ
• Jo DY
• Song KS
• Kim S

Abstract

Solid pseudopapillary tumor of the pancreas (SPTP) is a rare primary pancreatic tumor of an unknown etiology that is usually diagnosed in adolescent girls and young women. Most SPTPs are considered to be benign and only rarely metastasize. We report here on a 27-year old woman with recurrent SPTP with involvement of both the spleen and left kidney at the time of the initial diagnosis, and with aggressive behavior. In July 1995, she was admitted with abdominal discomfort and mass. She underwent exploratory laparotomy with distal pancrea tectomy, left nephrectomy and splenectomy, and was diagnosed with SPTP with invasion to both the spleen and left kidney. In June 2001, she again presented with abdominal pain and was diagnosed as having recurrence of the tumor. She underwent mass excision and omentectomy. Then she was lost to follow-up. In November 2005, she presented once again with an abdominal mass and was diagnosed with recurred SPTP, which formed a huge intraperitoneal mass with peritoneal seeding and the tumor showed multiple metastases in the liver. She is currently being treated conservatively.

Keyword

Solid pseudopapillary tumor; Pancreas; Neoplasm metastasis

MeSH Terms

Abdominal Pain
Adolescent
Adult
Diagnosis
Female
Humans
Kidney*
Laparotomy
Liver
Lost to Follow-Up
Neoplasm Metastasis
Nephrectomy
Pancreas*
Recurrence
Spleen*
Splenectomy

Figure

• 

  Fig. 1 Photomicrographs of the mass demonstrate solid and pseudopapillary tumor nests invading through the tumor capsule into the pancreas parenchyma on the low power view (A: hematoxylin and eosin, ×40), and pseudopapillary patterns on the high power view (B: ×200).

• 

  Fig. 2 CT scan of the abdomen shows multiple large hypoattenuating masses that involve entire liver, and there is a large mass with mild heterogenous enhancement in the left upper abdomen.

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