Asian Spine J.  2015 Jun;9(3):452-455. 10.4184/asj.2015.9.3.452.

Hemophilia A in a Senior Patient: A Case Report of Spinal Epidural Hematoma as First Presentation

Affiliations
  • 1Department Orthopedics, Seoul Sacred Heart General Hospital, Seoul, Korea. adkajs@hanmail.net

Abstract

Hemophilia A is a hereditary coagulation disorder. Most cases are diagnosed at birth or at least during childhood. A spontaneous spinal epidural hematoma was developed in a 74-year-old male patient who hadn't had a family or past medical history of bleeding disorders. On magnetic resonance imaging, epidural hematoma at L1-2 was accompanied by spinal stenosis at L4-5 and spondylolytic spondylolisthesis at L5. Hematoma evacuation and surgery for distal lumbar lesions were performed at once. After transient improvement, complete paraplegia was developed due to redevelopment of large epidural hematomas at L1-2 and L4-S1 which blocked epidural canal completely. Emergency evacuation was performed and we got to know that he had a hemophilia A. Factor VIII was 28% of normal value. Mild type hemophilia A could have not been diagnosed until adulthood. Factor VIII should have been replaced before the surgical decompression.

Keyword

Hemophilia A; Hematoma; Epidural; Spinal; Spontaneous; Senior

MeSH Terms

Aged
Blood Coagulation Disorders, Inherited
Decompression, Surgical
Emergencies
Factor VIII
Hematoma
Hematoma, Epidural, Spinal*
Hemophilia A*
Hemorrhage
Humans
Magnetic Resonance Imaging
Male
Paraplegia
Parturition
Reference Values
Spinal Stenosis
Spondylolisthesis
Factor VIII
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