Korean J Med.  2013 Jan;84(1):1-5.

Current Status of Primary Glomerulonephritis

• Chae DW

Abstract

Recent change in major indication for renal biopsy from nephrotic syndrome to asymptomatic urinary abnormality (AU) in Korea makes IgA nephropathy the most common biopsy-confirmed glomerulonephritis (GN). Beside from the most common manifestation of AU, a significant portion (22%) of IgA nephropathy (IgAN) patient revealed the nephrotic-range proteinuria. About 1/3 of patients with minimal change disease (MCD), membranous nephropathy (MN) and focal segmental glomerulosclerosis (FSGS) presented with AU. In elderly patient (> 60 years), the proportion of cresentic glomerulonephritis, MN, and FSGS increased, while the prevalence of IgAN decreased compared to younger patients. MCD showed no change based on old age. GN was the third most common cause of ESRD constituting 11-15% of cases. ESRD patients from GN start dialysis younger and live longer on dialysis compared to diabetic and hypertensive patients in Korea.

Keyword

Korea; Glomerulonephritis; Manifestations elderly; ESRD

MeSH Terms

Aged
Biopsy
Corneal Dystrophies, Hereditary
Dialysis
Glomerulonephritis
Glomerulonephritis, IGA
Glomerulonephritis, Membranous
Glomerulosclerosis, Focal Segmental
Humans
Kidney Failure, Chronic
Korea
Nephrosis, Lipoid
Nephrotic Syndrome
Prevalence
Proteinuria
Corneal Dystrophies, Hereditary
Glomerulosclerosis, Focal Segmental