Korean J Nephrol.  2000 Sep;19(5):972-976.

A Case of Rhabdomyolysis, Acute Renal Failure, and Acute Hepatitis Due to Carp Bile Ingestion

• Yeo DG
• Park JK
• Yoon WC
• Jung YD
• Kim HJ
• Cho SJ
• Lee IH
• Ahn KS
• Kim YJ

Abstract

Sevral cases of acute renal failure and acute hepatitis after ingestion of raw carp gall bladder have been reported. We experienced for the first time 1 case of acute renal failure and acute hepatitis associated with rhabdomyolysis, which has not been seen in previous studies, after ingestion of the raw carp gall bladder. Serum creatine phosphokinase, myoglobin and urine myoglobin were increased and 99mTc-MDP bone scan showed diffusely increased uptake of isotope in soft tissue of whole body. The other laboratory data corresponded to acute tubular necrosis and acute toxic hepatitis. The kidney pathology showed the recovery phase of acute tubular necrosis. Etiologic factor for rhabdomyolysis was not found except carp gall bladder. We considered that carp gall bladder was etiologic factor for rhabdomyolysis and that rhabdomyolysis acted as agravatting factor for developing acute tubular necrosis due to carp bile toxicity in this case.

Keyword

Aacute tubular necrosis; Acute hepatitis; Raw carp gall bladder; Rhabdomyolysis

MeSH Terms

Acute Kidney Injury*
Bile*
Carps*
Creatine Kinase
Drug-Induced Liver Injury
Eating*
Hepatitis*
Kidney
Myoglobin
Necrosis
Pathology
Rhabdomyolysis*
Technetium Tc 99m Medronate
Urinary Bladder
Creatine Kinase
Myoglobin
Technetium Tc 99m Medronate