Korean J Med.  2003 Nov;65(Suppl 3):S859-S862.

A case of pernicious anemia with early gastric cancer

Affiliations
  • 1Department of Internal Medicine, Seonam University College of Medicine, Gwangju, Korea. mrpark21@wonkwang.ac.kr
  • 2Department of Pathology, Seonam University College of Medicine, Gwangju, Korea.
  • 3Department of Internal medicine, Wonkwang University School of Medicine, Iksan, Korea.

Abstract

Pernicious anemia is caused by the absence of intrinsic factor from autoimmune destruction of parietal cells. Patients with pernicious anemia are predisposed to the development of gastric cancer. We report here a case of pernicious anemia with early gastric cancer. A 65 year old woman was presented with severe anemia and glossitis. Her serum cobalamin level was low, and serologic test to anti-intrinsic factor antibody and anti-parietal cell antibody were positive. Gastroscopic examination revealed an early gastric cancer and type A atrophic gastritis. This patient underwent radical subtotal gastrectomy and received daily oral vitamin B12 replacement.

Keyword

Anemia; Pernicious; Stomach Neoplasms

MeSH Terms

Aged
Anemia
Anemia, Pernicious*
Female
Gastrectomy
Gastritis, Atrophic
Glossitis
Humans
Intrinsic Factor
Rabeprazole
Serologic Tests
Stomach Neoplasms*
Vitamin B 12
Intrinsic Factor
Vitamin B 12
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