Korean J Leg Med.  2008 May;32(1):68-71.

Change of Surname?: An application of Y-STR Haplotyping

Affiliations
  • 1Department of Forensic Medicine, Central District Office, NISI, Daejeon 305-348, Korea. cns6999@nisi.go.kr

Abstract

Y-STR haplotyping is a powerful forensic and anthropological tool for identifying male lineages. We used high-resolution Y-STR haplotyping to evaluate the possibility of an ancestral relationship between two individuals with the different surname. Of the 17 Y-STRs genotyped, 16 had identical alleles in two individuals, except for an unambiguously sporadic mutation (one-step mutation) at DYS385 locus. The common allele 11.1 (U3Ains) at DYS439 locus was also observed in these two individuals. Sequencing analysis of these alleles of two samples demonstrated an A insertion at base 3 upstream from the repeat region's first GATA motif. These findings suggested that two individuals were paternally related, even if male individuals live with different surname.

Keyword

Y-STR; surname; haplotypes; mutation

MeSH Terms

Alleles
Haplotypes
Humans
Male
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